A Comparative Study of Classifier Ensembles for Karyotyping
Authors: Iñigo Barandiaran and Grégory Maclair and Izaro Goienetxea and Carlos Jauquicoa and Manuel Graña
Date: 12.09.2012
Abstract
The karyotyping step is essential in the genetic diagnosis process, since it allows the genetician to see and interpret patient's chromosomes. Today, this step of karyotyping is a time-cost procedure, especially the part that consists in segmenting and classifying the chromosomes by pairs. This paper presents a compartive study of image classication of banded human chromosomes for automated karyotyping (AKS), by using classier ensembles. The goal of this contribution is to propose and evaluate a solution to automate the karyotyping, from microscope images to the obtention of the classied chromosomes. For this purpose, we have evaluated several approaches based on classier ensembles trying to nd a solution that shows better trade-o between accuracy and computational cost.
BIB_text
author = {Iñigo Barandiaran and Grégory Maclair and Izaro Goienetxea and Carlos Jauquicoa and Manuel Graña},
title = {A Comparative Study of Classifier Ensembles for Karyotyping},
pages = {1400-1407},
volume = {243},
keywds = {
Karyotyping, classier ensembles, Pattern Recognition
}
abstract = {
The karyotyping step is essential in the genetic diagnosis process, since it allows the genetician to see and interpret patient's chromosomes. Today, this step of karyotyping is a time-cost procedure, especially the part that consists in segmenting and classifying the chromosomes by pairs. This paper presents a compartive study of image classication of banded human chromosomes for automated karyotyping (AKS), by using classier ensembles. The goal of this contribution is to propose and evaluate a solution to automate the karyotyping, from microscope images to the obtention of the classied chromosomes. For this purpose, we have evaluated several approaches based on classier ensembles trying to nd a solution that shows better trade-o between accuracy and computational cost.
}
isbn = {978-1-61499-104-5},
isi = {1},
date = {2012-09-12},
year = {2012},
}